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For Healthcare Professionals

Information for Healthcare Professionals about Bimuno®.

Discover more about Bimuno® and how it could benefit your patients to help them feel healthier and happier in their lives.

Bimuno® is a revolutionary range of food supplements containing a unique active ingredient; B-GOS®. Bimuno® naturally feeds and stimulates the growth of good bacteria in the gut.

About Bimuno®

Bimuno® is far more than a great galacto-oligosaccharide, it is a patented carbohydrate complex (B-GOS®) backed by a substantial programme of scientific research and clinically proven to provide a wide range of health benefits.

It is the only 2nd generation prebiotic and as such offers additional functionality over and above its bifidogenic effect. Unlike many probiotics, Bimuno® reaches the lower gut intact.

Clinical studies demonstrate that Bimuno® is highly effective at rebalancing the gut microbiota composition1,2,5,6 as well as having direct and indirect immunomodulatory effects2,5,6.

Studies have also demonstrated Bimuno® to have the most powerful bifidogenic effect compared to another commercially available prebiotic1.

Globally Recognised Innovation

Bimuno® is recognised as the most advanced carbohydrate complex of its kind having been designed and developed in collaboration with some of the world’s most respected scientific research institutes. 

The advanced technology behind Bimuno® and the brand itself is protected by worldwide patents and trademarks.

Bimuno® is the result of intensive research & development including peer reviewed, clinical trials conducted in collaboration with the University of Reading’s Food Microbial Sciences Unit and other globally recognized research institutes and as a result is a multi-functional supplement based around a unique and patent-protected, galacto-oligosaccharide (B-GOS®) formulation.

In-Vitro, Animal and Human intervention studies prove that Bimuno® has unique properties.

How Bimuno® works

  1. Bimuno® reaches the small intestine intact
  2. In the small intestine Bimuno® inhibits the adhesion of GI pathogenic bacteria via the action of blocking their attachment to the epithelium. This helps prevent pathogenic colonisation3,4
  3. In the large intestine Bimuno® is metabolised by specific beneficial bacteria belonging to the Bifidobacterium species (infantis, logum & bifidum). The result is a change in pH balance which favours the growth of beneficial bacteria at the expense of pathogenic bacteria, resulting in a positive change in the gut microbiota1,2,5,6
  4. There is evidence that Bimuno® has a positive effect on the innate immune system resulting from an increase in phagocytosis and NK cell activity2
  5. There is also a positive effect of Bimuno® on the adaptive immune system resulting from the increase of anti-inflammatory cytokines, a reduction in pro-inflammatory cytokines as well as other markers of inflammation2,5,6
  6. The net effect is that it helps maintain gut health and general well-being.

References:

  1. Depeint F et al. Am J Clin Nutr 2008;87:785-91.
  2. Vulevic J et al. Am J Clin Nutr 2008;88:1438-46.
  3. Tzortzis G et al. J. Nutr 2005;135:1726-1731.
  4. Searle LEJ et al. Journal of Medical Microbiology 2009;58:37-48.
  5. Vulevic J et al. J. Nutr 2013;143:324-331.
  6. Vulevic J, et al. Br J Nutr 2015;114:586-95.
  7. Schmidt K et al. Psychopharmacology DOI 10.1007/s00213-014-3810-0.

Prebiotics vs. Probiotics

Learn more about the crucial part both prebiotics and probiotics play in not only digestive health, but overall health and wellbeing...

What Are Prebiotics?

Prebiotics are classified as non-digestible food ingredients that can be utilised by probiotics

What Are Probiotics?

Probiotics are defined as ‘live microorganisms’, which – when administered in adequate quantities – confer a health benefit to the host.

Prescribing Them to Patients

The modulation of the gut microbiome, using prebiotics and probiotics, may offer new therapeutic strategies for many diseases.

Shop Bimuno®

Easy | Healthy | Happy

Bimuno® DAILY

A daily supplement for individuals who wish to support their gut health and overall well-being.

Bimuno® IBAID

Bimuno® pastilles containing an optimum dose for people experiencing IBS symptoms.

Bimuno® TRAVELAID

Bimuno® pastilles can help with the symptoms of travellers' diarrhoea if taken before & during travel.

Sample Requests

Product samples are available for healthcare professionals. In order to request a sample, please fill out the form below and we will contact you shortly.

Scientific Studies

B-GOS®, commercially available as Bimuno®, is the result of intensive research & development dating back from 2000 and conducted in collaboration with the University of Reading’s Food Microbial Sciences Unit and other globally recognized research institutes.

The result of this research was the development of a multi-functional supplement based around a unique and patent-protected, galactooligosaccharide formulation. It is a 2nd generation prebiotic and as such offers additional functionality over and above its bifidogenic effect.

Human intervention studies show that Bimuno®’s unique properties go well beyond its advanced prebiotic action, via a triple mode of action in the gut. It has been proven to:

  • Positively rebalance gut microbiota by selectively promoting beneficial bacteria.
  • Prevent adhesion of bacterial pathogens, thereby helping protect against infections.
  • Help combat chronic inflammation via its action with the immune system.

Research is on-going and is mainly focusing in the exciting area of chronic inflammation aimed at combating the many debilitating long term illnesses.

Waking Cortisol Levels

The effect of prebiotics on the secretion of the stress hormone, cortisol.

Schmidt et al, 2015

Gut microbiota, immune parameters & metabonomics

Positive modulation of microbiota in elderly.

Vulevic et al, 2008

Reduction in markers of metabolic syndrome

Altering colonic microflora of overweight individuals.

Vulevic et al, 2008

Reduction in symptoms of Travellers’ Diarrhoea

Effectiveness of B-GOS® on incidence of travellers’ diarrhoea (TD) in healthy subjects.

Drakoularakou et al, 2009

Irritable Bowel Syndrome

Effectiveness of B-GOS® in changing colonic microflora and improving symptoms in IBS sufferers.

Silk et al, 2009

Immune Parameters & Gut microflora

Effect of a B-GOS®) on immune function and faecal microflora composition in elderly.

Vulevic et al, 2008

Prebiotic evaluation of B-GOS®

Assesment of the prebiotic potential of a B-GOS®in healthy humans.

Depeint et al, 2008

Reduction of salmonella enterica serovar typhimurium

Hypothese that Bimuno® may confer some protection in the murine host from S. Typhimurium infection.

Searle et al, 2009

Fermentation properties & activity on microbiota parameters

B-GOS® assessed in-vitro and in a parallel continuous randomised pig trial.

Tzortzis et al, 2005

Resources


FAQs

Recommending Bimuno®

  • What is Bimuno®?

    Bimuno® is a daily food supplement containing the unique, active ingredient B-GOS® (Galactooligasaccharide). B-GOS® works by selectively increasing the level of bifidobacteria and other health-promoting bacteria found in the gut.

    There are three different Bimuno® products. These are: Bimuno® Daily, Bimuno® Ibaid ,  Bimuno®  Travelaid.

  • What does Bimuno® do?

    Bimuno® naturally feeds and increases the friendly bacteria in your gut.

    Formulated with the knowledge that more than 60% of the immune system is in the gut, it works with your own natural systems to influence general health & wellbeing.

  • Who can take Bimuno®

    Bimuno® is for anyone who wishes to maintain their digestive health and general wellbeing.  Bimuno® Travelaid can help with the symptoms of travellers' diarrhoea if taken before & during travel.

  • Is Bimuno® suitable for children?

    Yes, children can take Bimuno®.

    Bimuno® Daily is suitable for children aged 4 years and above. Children aged 4-11 years should take half a sachet.

    Bimuno® IBAID is suitable for children aged 12 and above.

    Bimuno® TRAVELAID is suitable for children aged 12 and above.

    Young children should always take Bimuno® under the supervision of an adult.

  • What is the difference between Bimuno® Daily, Bimuno® IBAID and Bimuno® Travelaid?

    All Bimuno® products contain the unique active ingredient B-GOS® (Galactooligasaccharide).

    Bimuno® Daily is a powder, which comes in an easy to use sachet. Just pour one sachet of Daily into your tea, coffee, juice or other drink, or sprinkle it over food every day.

    Bimuno® IBAID – is in a chewable pastille form. A daily dose of Ibaid (2 pastilles) contains a lower dose than our Daily product and is recommended if you have sensitive digestion.

    Bimuno® TRAVELAID – is in a chewable pastille form.  It is recommended that you take three pastilles daily, starting 7 days before you travel to countries where there is an increased risk of developing travellers’ diarrhoea and that you continue taking it whilst you are away.

  • How should my patients take Bimuno®?

    Bimuno® DAILY – Take one sachet daily, dissolved in tea, coffee, juice or other drink, or sprinkled over food.

    Bimuno® IBAID – Take two pastilles, chewing each one separately and thoroughly before swallowing. For best results, take the two pastilles at the same time of day.

    Bimuno® TRAVELAID – Recommended for when travelling to countries where there is an increased risk of developing travellers’ diarrhoea Take three pastilles daily, starting 7 days before travel and continuing whilst away. For best results, take the three pastilles at the same time of day.

  • Is Bimuno® a medicine?

    Bimuno® is not a medicine and is not intended to prevent or treat medical conditions or their symptoms.

    Bimuno®’s legal status is that of a food supplement. It is not available on prescription and is free from any pharmacy supervisory restrictions. Healthcare Professionals can recommend Bimuno® to their customers and patients.

  • When should my patients take Bimuno®?

    Bimuno® can be taken any time of the day, as part of a daily routine. For maximum benefit, patients should try to take it around the same time every day.

  • How often should my patients take Bimuno®?

    They only need to take Bimuno® once a day. Bimuno® is best taken regularly as part of a daily routine, not just when the patient is feeling the symptoms of gastrointestinal discomfort (e.g. pain, bloating, diarrhoea, discomfort), but long term in order to feel the benefits to their overall health & wellbeing.

  • What should my patients expect when taking Bimuno® for the first time?

    When they take Bimuno® for the first time, it will take 3 days to start feeding their bifidobacteria. Between days 4 and 7, they may experience some gurgling in their stomach. This is a good sign as its means Bimuno® is beginning to change the gut microbiota, which is the community if microorganisms that live in the digestive system.

    Published studies have shown that, with daily use, the majority of Bimuno® users experience an increase in their gut bifidobacterial within 7 days, although individual responses may vary.

  • Can Bimuno® help with sleep disorders?

    The BBC programme “The Truth about sleep” showed the impact on Dr Mosley of consuming Bimuno® DAILY Powder.

    The programme explained the impact of improving fibre intake and the positive effect that this has on the good bacteria in your gut and inferred that this may improve sleep patterns.

    In the programme Dr Mosley discussed how his sleep patterns had improved whilst taking Bimuno® in the evening before going to sleep. It should be noted that no formal clinical investigations have been conducted to assess the impact of Bimuno® on sleep patterns.

  • Are there any side-effects with taking Bimuno®?

    Within the first week of taking Bimuno®, your patients may experience stomach gurgling and rumbling which then subsides. This is a good sign, as it means Bimuno® is working.

  • Is it safe to take Bimuno® long term?

    Yes, it is safe to take Bimuno® long term. In fact, we recommend that your patients continue taking Bimuno® even after their symptoms have gone away. By taking Bimuno® as part of their daily routine, they ensure an adequate number of beneficial bacteria thrive in their gut and this helps maintain a healthy digestive system.

  • Where can my customers or patients buy Bimuno® from?

    In the UK, the complete Bimuno® range is available online at Bimuno.com as well as branches of Boots, Holland & Barrett & smaller chemists and healthfood shops nationwide.

Prebiotic facts

  • What is the difference between probiotics and prebiotics?

    Probiotics are beneficial live bacteria which when taken in adequate quantities can confer a health benefit. They are commercially available as dietary supplements or foods.

    Prebiotics are carbohydrates that act as food for the gut’s probiotic (beneficial) bacteria. Prebiotics are  digested in the stomach or small intestine and therefore reach the colon where they exert a positive effect on the resident beneficial probiotic bacteria so as to confer a health benefit.

  • What are the benefits of prebiotics over probiotics?

    As probiotic supplements and foods contain live bacteria, they need to survive the passage through the upper gastrointestinal tract, the acidity of the stomach, secretions of the small intestine and then compete with existing bacteria for colonisation sites in the large intestine (colon). According to research published by the Food Standards Agency in 2005, not all commercially available probiotic products can claim to survive this passage and colonise at an effective rate.

    Prebiotics are ‘non-digestible’. This means that they reach the large intestine where they exert a beneficial effect on the resident beneficial probiotic bacteria so as to confer a health benefit. The latest in Key Opinion Leader thinking is that it is preferable to feed our indigenous beneficial gut microbiota (prebiotic effect) as opposed to adding manufactured strains of beneficial bacteria into our eco-system (probiotic effect).

  • How many different types of Prebiotics are there?

    Prebiotics fall into three categories. These are Fructo-oligosaccharides (FOS), Galacto-oligosaccharides (GOS) and Lactulose.

    Prebiotics are either 1st generation or 2nd generation. FOS, GOS and Lactulose prebiotics are classed as 1st generation. B-GOS® is classified 2nd generation prebiotic.

    1st generation prebiotics are selective at the genus level. In other words they are fermented at the family group level (e.g. by Bifidobacteria or Lactobacillus) and produce a prebiotic effect (increase the number and activity of the beneficial bacteria) or bifidogenic effect (increase the number and strength of the Bifidobacteria).

    2nd generation prebiotics are tailor made to offer selectivity at species level (e.g. by Bifidobacterium bifidum) and also offer added functionality i.e. anti-adhesive or anti-pathogenic properties.

  • How does Bimuno® differ from other prebiotics?

    Bimuno® is the result of intensive research & development including peer reviewed, clinical trials conducted in collaboration with the University of Reading’s Food Microbial Sciences Unit and other globally recognized research institutes.

    Bimuno® was first launched in the UK market as a 2nd generation prebiotic with documented added functionality over other prebiotics and also probiotic foods and supplements.

    Human intervention studies show that Bimuno®’s unique properties go well beyond its bifidogenic action.

    Bimuno® acts via a triple mode of action in the gut. It has been proven to:

    1. Positively rebalance gut microbiota by selectively promoting health-promoting bacteria (bifidobacteria)
    2. Prevent adhesion of bacterial pathogens, thereby helping protect against infections
    3. Help combat chronic inflammation via its action with the immune system.

Pre-existing conditions, intolerances and special diets

  • Is Bimuno® suitable for diabetics?

    Bimuno® has been available in the UK since March 2007. To date, there have been no reported cases of adverse reactions involving diabetic patients. The content of Bimuno®’s monosaccharides (glucose and galactose) is clinically modest.

  • Can my patients take Bimuno® with a Probiotic?

    Yes, they can take Bimuno® alongside a probiotic supplement.

  • Can my patients take Bimuno® if they are taking prescribed medicines?

    Bimuno® is a food supplement and not a medicine. On the basis of our scientific knowledge there should be no effect on other medications taken alongside Bimuno®.

  • Can my patients take Bimuno® if they are pregnant or breast feeding?

    Yes, they can. Bimuno® is a food supplement and not a medicine. It is not absorbed but transits through the gut to the large intestine (colon).

  • Will Bimuno® interfere with chronic medication?

    Bimuno® is a food supplement and not a medicine; to the best of our knowledge, there are no described contraindications or interactions with medicines.

  • Can Bimuno® be taken whilst undergoing chemotherapy or radiotherapy?

    Although we have not had any studies looking at the safety of Bimuno® in cancer patients during or after chemotherapy and radiotherapy, the scientific evidence suggests that it is safe to take supplements like Bimuno® during chemotherapy and radiotherapy.

    Bimuno® is a food supplement and not a medicine; to the best of our knowledge, there are no described contraindications or interactions with medicines.

  • Is Bimuno® suitable to take if my patients have a pre-existing medical condition such Coeliac Disease, SIBO,IBD etc.?

    Bimuno® is generally regarded as safe to take even if you have existing medical conditions.  However, if you would like to discuss this further with our in-house medical expert, please complete the contact form and we will arrange for them to contact you.

  • Can I take Bimuno® if I suffer from Small Intestinal Bacterial Overgrowth (SIBO)?

    There are currently no scientific studies on the safety and efficacy of Bimuno® in people with Small Intestinal Bacterial Overgrowth (SIBO) and therefore we cannot comment on its use in this condition.However, from the scientific literature there is no evidence to suggest that it is harmful to take products similar to Bimuno® with other treatments for SIBO.  For this reason, we would suggest that you discuss this with your healthcare professional before taking Bimuno®.

  • Is Bimuno® suitable for people suffering from milk allergy?

    Bimuno® Daily does contain milk proteins – Betalactoglobulin and Casein.

    Bimuno® IBAID and TRAVELAID have been analysed for milk proteins and the results are below the limits of detection.

    On all our packs we are identify allergens in bold in our ingredients list.

  • Is Bimuno® suitable for people suffering from lactose intolerance?

    Bimuno® contains lactose. However, the lactose content is well below that considered safe in most lactose intolerant people by the British Dietic Associate (BDA) and the European Food safety Authority (EFSA).

    Bimuno® levels of lactose compared to official definitions of low lactose:

    Product (Single Dose/g)

    Lactose content (Grams)

    EFSA Guidelines¹

    BDA Guidance²

    Bimuno® DAILY

    1.5g

    <12g

    <13g

    Bimuno® IBAID

    0.36g

    <12g

    <13g

    Bimuno® TRAVELAID

    0.71g

    <12g

    <13g

    References:

    ¹https://www.efsa.europa.eu/en/efsajournal/pub/1777

    ²http://onlinelibrary.wiley.com/doi/10.1111/j.1365-277X.2012.01242.x/full

  • Is Bimuno® suitable for vegetarians?

    Bimuno® Powder is suitable for vegetarians.
    Neither Bimuno® IBAID nor TRAVELAID are suitable for vegetarians as they contain bovine gelatine.

  • Is Bimuno® suitable for vegans?

    No, Bimuno® is not suitable for vegans as it contains lactose.

  • Is Bimuno® suitable for Kosher and Halal diets?

    Bimuno® IBAID and TRAVELAID are suitable for Kosher & Halal diets.
    Bimuno® Daily is not.

  • Is Bimuno® gluten free?

    Yes, Bimuno® is gluten free.

  • Does Bimuno® contain artificial colours or flavourings?

    Bimuno® is free from artificial colours, flavours and preservatives.

  • Can I recommend Bimuno® for digestive health maintenance in Irritable Bowel Syndrome (IBS) sufferers?

    Bimuno® is not a medicine and is not indicated for prevention or treatment of medical conditions or their symptoms.

    However, Bimuno® is safe for patients suffering from IBS. In fact, Bimuno®’s unique action and superior efficacy profile has demonstrated effectiveness in enhancing bifidobacterial levels and helping maintain gut health in IBS sufferers. There are also a number of Bimuno® scientific studies demonstrating a significant increase in the beneficial bacteria, Bifidobacteria, which are normally found in reduced numbers in IBS sufferers.

    Due to the condition itself, your patients may find they have a more sensitive digestion and so should either take the full dose of Bimuno® IBAID (i.e. two pastilles) or half a sachet of Bimuno® Daily.

  • Can my patients take Bimuno® if they are on a low FODMAP diet?

    Bimuno® is not classed as a FODMAP, however as a low FODMAP diet has been shown to decrease the levels of bifidobacteria in IBS sufferers, Bimuno® may be a useful addition to a low FODMAP diet.

Disclaimer

This section is an information and educational resource for healthcare professionals, scientists, researchers and journalists. It is not intended for consumers. If you wish to purchase Bimuno please click here